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 Formulary Chapter 5: Infections - Full Section
Notes:

To promote the appropriate use of antibiotics
-To avoid unnecessarily long courses
-to prevent the emergence and propogation of antimicrobial resistance
-to minimise the risk of Clostridium difficile infection

Antimicrobial Prescribing Guidelines - Primary Care

Antimicrobial Prescribing Guidelines - Adults Summary

Treatment          Surgical Prophylaxis
Bone & Joint Infections     Rationale for Prophylaxis
CNS Infections          Gentamicin Prophylaxis Dosing
Endocarditis          Cardiology Procedures
ENT Infections           General Surgery
Eye Infections                          Head & Neck Surgery
& Orbital Cellulitis               Obstetrics & Gynaecology
Gastrointestinal Infections   Orthopaedic Surgery
Genital Tract Infections     Urological Surgery
Respiratory Infections
Sepsis
Skin & Soft Tissue Infections
& Diabetic Foot Infections
UTIs
ED Supplement - Cellulitis

Antimicrobial Prescribing Guidelines - Paediatrics
Treatment
Orbital Cellulitis Guidelines
Neonatal sepsis - dosing chart
Neonatal sepsis guidelines (with meningitis)
IV antibiotic doses used on SCBU - quick reference guide
IV antibiotic doses in children from 1 month to 16 years - quick reference guide

Penicillin Allergy
For guidelines for prescribing in patients with documented allergy to penicillins, click here.

Dose Recommendations
- The doses recommended in the guidelines are for guidance ONLY.
- For elderly/renally-impaired patients, consult current BNF, ward pharmacist or Medicines Information (Ext: 3084)

Antimicrobial Medicines Code
- The Antimicrobial Medicines Code sets out the roles and responsibilities for healthcare professionals involved in the prescribing, supply and administration of antibiotics.
- The full version of the Antimicrobial Medicines Code can be found by clicking here
- Summary of Prescribing Standards (Section 3)
   - Is an antimicrobial indicated?
   - Ensure appropriate specimens are taken prior to starting therapy.
   - Choice of antibiotic should be based on local guidelines.
   - Include the duration (or review date) and the indication for treatment on the prescription chart
   - Review the need for antibiotics regularly, including switching from IV to PO treatment, according to the policy. Click here for details of the IV to PO Switch Policy.

OPAT Registration Form and Pathway

Microbiology Investigations
When ordering microbiology investigations please give relevent clinical details. The ways in which specimens are processed, the interpretation of the results and reporting of antimicrobial susceptibilities will vary to a very great extent, on the clinical details given.

CIVAS order form

 Useful Links

05.01 Antibacterial drugs
Summary of antibacterial therapy
Summary of antibacterial prophylaxis
05.01.01 Penicillins
05.01.01.01 Benzylpenicillin and phenoxymethylpenicillin
05.01.01.02 Penicillinase-resistant penicillins
05.01.01.03 Broad-spectrum penicillins
05.01.01.04 Antipseudomonal penicillins
05.01.01.05 Mecillinams
05.01.02 Cephalosporins, carbapenems and other beta-lactums
05.01.02.01 Cephalosporins
05.01.02.02 Carbapenems
05.01.02.03 Other beta-lactums antibiotics
05.01.03 Tetracyclines
Tigecycline
05.01.04 Aminoglycosides
05.01.05 Macrolides
05.01.06 Clindamycin
05.01.07 Some other antibacterials
Chloramphenicol
Fusidic acid
Vancomycin and teicoplanin
Daptomycin
Linezolid
Quinupristin and dalfopristin
Polymyxins
Rifaximin
Fidaxomicin
05.01.08 Sulphonamides and trimethoprim
05.01.09 Antituberculosis drugs
05.01.10 Antileprotic drugs
05.01.11 Metronidazole and tinidazole
05.01.12 Quinolones
05.01.13 Urinary-tract infections
05.02 Antifungal drugs
05.02.01 Triazole antifungals
05.02.02 Imidazole antifungals
05.02.03 Polyene antifungals
05.02.04 Echinocandin antifungals
05.02.05 Other antifungals
05.03 Antiviral drugs
05.03.01 HIV infection
Nucleoside reverse transcriptase inhibitors
Protease inhibitors
Non-nucleoside reverse transcriptase inhibitors
Other antiretrovirals
05.03.02 Herpesvirus infections
05.03.02.01 Herpes simplex and varicella-zoster infection
05.03.02.02 Cytomegalovirus infrection
05.03.03 Viral hepatitis
05.03.03.01 Chronic hepatitis B
05.03.03.02 Chronic hepatitis C
05.03.04 Influenza
05.03.05 Respiratory syncytial virus
05.04 Antiprotozoal drugs
05.04.01 Antimalarials
Treatment of malaria
Falciparum malaria (treatment)
Benign malarias (treatment)
Prophylaxis against malaria
Specific recommendations
Artemether with lumefabtrine
Chloroquine
Mefloquine
Primaquine
Proguanil
Pyrimethamine
Quinine
Tetracyclines
05.04.02 Amoebicides
05.04.03 Trichomonacides
05.04.04 Antigiardial drugs
05.04.05 Leishmaniacides
05.04.06 Trypanocides
05.04.07 Drugs for toxoplasmosis
05.04.08 Drugs for pneumocystis pneumonia
Treatment
Prophylaxis
05.05 Anthelmintics
05.05.01 Drugs for threadworms
05.05.02 Ascaricides
05.05.03 Drugs for tapeworm infections
Taenicides
Hydatid disease
05.05.04 Drugs for hookworms
05.05.05 Schistosomicides
05.05.06 Filaricides
05.05.07 Drugs for cutaneous larva migrans
05.05.08 Drugs for strongyloidiasis
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