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Harrogate & District NHS Foundation Trust
Harrogate & Rural District Clinical Commissioning Group
 
 
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 Formulary Chapter 2: Cardiovascular system - Full Chapter
Notes:
HDFT Guidelines on the management of stroke

Guidelines for the Management of Hyperglycaemia in Acute Coronary Syndrome (ACS)
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02.05  Expand sub section  Drugs affecting the renin-angiotensin system and some other antihypertensive drugs
02.05.01  Expand sub section  Vasodilator antihypertensive drugs
Hydralazine Hydrochloride
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Formulary
Red
Injection 20mg 
   
02.05.02  Expand sub section  Centrally acting antihypertensive drugs
Moxonidine
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Restricted Drug Restricted
Amber
Tablets 200micrograms
For use by a specialist only 
   
02.05.03  Expand sub section  Adrenergic neurone blocking drugs
02.05.04  Expand sub section  Alpha-adrenoceptor blocking drugs to top
Doxazosin
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Formulary
Green
Tablets 1mg, 2mg, 4mg 
   
02.05.04  Expand sub section  Phaeochromocytoma
02.05.05  Expand sub section  Drugs affecting the renin-angiotensin system
02.05.05  Expand sub section  Heart Failure
Valsartan (Diovan)
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Formulary
Green
Tablets 40mg; Capsules 80mg, 160mg

For heart failure post myocardial infarction only 
   
02.05.05.01  Expand sub section  Angiotensin-converting enzyme inhibitors (ACE inhibitors)
Ramipril
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First Choice
Green
Capsules 2.5mg 5mg 10mg 
Lisinopril
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Formulary
Green
Tablets 2.5mg 5mg 10mg 20mg 
   
Perindopril erbutine
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Formulary
Green
Tablets 2mg 4mg
For use by specialists in stroke patients only
Perindopril Erbutine only 
   
02.05.05.02  Expand sub section  Angiotensin-II receptor antagonists to top
Losartan Potasium (Cozaar)
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First Choice
Green
Tablets 25mg, 50mg 
Candesartan Cilexetil (Amias)
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Restricted Drug Restricted
Green
Tablets 4mg 8mg 16mg 
   
Irbesartan (Aprovel )
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Restricted Drug Restricted
Green
Tablets 75mg 150mg
For use by specilaists only for diabetic nephropathy 
   
Sacubitril/valsartan  (Entresto)
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Formulary
Amber
To be prescribed in line with NICE TA388 
Link  TA 388: Sacubitril valsartan for treating symptomatic chronic heart failure with reduced ejection fraction
   
02.05.05.03  Expand sub section  Renin inhibitors
Aliskiren (Rasilez)
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Restricted Drug Restricted
Amber
Tablets 150mg
For use by Renal Unit patients or on the advice of a specialist only 
   
 ....
 Non Formulary Items
Bosentan  (Tracleer®)

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Non Formulary
 
Captopril

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Non Formulary
 
Captopril and Hydrochlorothiazide  (Capozide)

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Non Formulary
 
Captopril and Hydrochlorothiazide  (Co-zidocapt)

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Non Formulary
 
Clizazpril  (Vascace®)

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Non Formulary
 
Clonidine Hydrochloride  (Catapres)

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Non Formulary
 
Clonidine Hydrochloride  (Dixarit)

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Non Formulary
 
Diazoxide  (Eudemine®)

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Non Formulary
 
Doxazosin  (Cardura XL)

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Non Formulary
Black
MR Tablets 4mg, 8mg
 
Enalapril Meleate

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Non Formulary
 
Enalapril Meleate and Hydrochlorothiazide  (Innozide)

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Non Formulary
 
Fosinopril Sodium

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Non Formulary
 
Fosinopril Sodium  (Staril®)

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Non Formulary
 
Guanethidine Monosulphate  (Ismelin®)

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Non Formulary
 
Iloprost

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Non Formulary
 
Iloprost  (Vantavis)

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Non Formulary
 
Imidapril Hydrochloride  (Tanatril®)

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Non Formulary
 
Indoramin  (Baratol®)

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Non Formulary
 
Indoramin  (Doralese®)

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Non Formulary
 
Lisinopril and Hydrochlorothiazide  (Carace Plus)

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Non Formulary
 
Lisinopril and Hydrochlorothiazide  (Lisicostad)

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Non Formulary
 
Lisinopril and Hydrochlorothiazide  (Zestoretic)

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Non Formulary
 
Methyldopa

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Non Formulary
 
Minioxidil  (Loniten®)

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Non Formulary
 
Moexipril Hydrochloride  (Perdix®)

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Non Formulary
 
Olmesartan Medoxomil  (Sevikar®)

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Non Formulary
 
Perindopril Erbumine and Indapamide  (Coversyl plus)

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Non Formulary
 
Phenoxybenzamine Hydrochloride

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Non Formulary
 
Phenoxybenzamine Hydrochloride  (Dibenyline)

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Non Formulary
 
Phentolamine Messilate  (Rogitine)

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Non Formulary
 
Prazosin

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Non Formulary
 
Quinapril

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Non Formulary
 
Quinapril  (Accupro®)

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Non Formulary
 
Quinapril and Hydrochlorothiazide  (Accuretic)

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Non Formulary
 
Ramipril and Felodipine  (Triapin)

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Non Formulary
 
Sildenafil  (Revatio®)

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Non Formulary
 
Sildenafil  (Viagra®)

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Non Formulary
 
Sitaxentan Sodium  (Thelin®)

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Non Formulary
 
Sodium Nitroprusside

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Non Formulary
 
Terazosin

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Non Formulary
 
Terazosin  (Hytin®)

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Non Formulary
 
Tolazoline

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Non Formulary
 
Trandolapril  (Gopten)

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Non Formulary
 
Trandolapril and Verapamil  (Tarka)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber

Medicines which are suitable to be prescribed in primary care only after specialist recommendation. Ongoing prescribing by primary care includes titration of dose and assessment of efficacy. There is no need for ongoing monitoring other than for general adverse effects as listed in the BNF & SPC.  

Amber Shared Care

Medicines which are suitable to be prescribed in primary care only after specialist recommendation only under a shared care protocol once the patient has been stabilised. Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must be approved by the Harrogate & Rurual District Area Prescribing Committee (HaRD APC).   

Black

Medicines which the Harrogate & Rural District Area Prescribing Committee (HaRD APC) has reviewed and does not recommend for use at present based on a review of clinical and/or cost effectiveness data.   

Green

Medicines suitable for routine use and can be prescribed within primary care within their licensed indication in accordance with nationally recognised formularies e.g. BNF, BNF for Children, Palliative Care Formulary. Primary care prescribers take full responsibility for prescribing.  

Grey

Medicines which the Harrogate & Rural District Area Prescribing Committee (HaRD APC) have not yet reviewed.   

Red

Medicines for hospital use only. The responsibility for initiation and monitoring treatment should rest with an appropriate hospital clinician. The drug should be supplied by the hospital for the duration of the treatment course. Primary care prescriber initiation or continuation of treatemnt is not recommended.  

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