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Harrogate & District NHS Foundation Trust
Harrogate & Rural District Clinical Commissioning Group
 
 
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 Formulary Chapter 2: Cardiovascular system - Full Chapter
Notes:
HDFT Guidelines on the management of stroke

Guidelines for the Management of Hyperglycaemia in Acute Coronary Syndrome (ACS)
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02.06  Expand sub section  Nitrates, calcium-channel blockers, and potassium-channel activators
02.06  Expand sub section  Angina
Trimetazidine (Unlicensed)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted MR Tablets 35mg

For use by specialists as last line therapy for unstable angina 
   
02.06.01  Expand sub section 
 note 


Glyceryl Trinitrate
View adult BNF View SPC online View childrens BNF
Formulary
Green
Spray 400micrograms/dose; Buccal tablets 2mg, 3mg, 5mg; Sublingual tablets 500micrograms; Injection 50mg/50ml (hospital only) 
Link  BP Management Protocol following Acute Haemorrhagic Stroke
Link  BP Management Protocol to lower BP prior to IV Thrombolysis for Acute Ischaemic Stroke
   
Isosorbide Mononitrate
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
  • Consider isosorbide mononitrate as monotherapy for stable angina if beta blockers and calcium channel blockers cannot be tolerated or both are contraindicated.
  • Consider adding isosorbide mononitrate if symptoms of stable angina are not controlled with beta blocker or calcium channel blocker monotherapy and the other option (calcium channel blocker or beta blocker) is contraindicated or not tolerated.

See NICE CG126: stable angina

 
Link  NICE CG126: Stable angina
Link  Use of Nitrates in Stable Angina
   
Isosorbide Dinitrate
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
Injection 10mg/10ml
For use in Cardiac Unit only 
   
02.06.02  Expand sub section  Calcium-channel blockers
Amlodipine
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First Choice
Green
Tablets 5mg, 10mg 
Diltiazem Hydrochloride (Tildiem)
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Formulary
Green
MR tablets (SR) 60mg, 90mg, 120mg
(twice daily dosing)

MR capsules (LA) 200mg, 300mg
(once daily dosing)

Prescribe by brand 
   
Diltiazem Hydrochloride (Adizem)
View adult BNF View SPC online View childrens BNF
Formulary
Green
SR Capsules 90mg, 120mg, 180mg
(twice daily dosing)

XL Capsules 120mg, 180mg, 240mg, 300mg
(once daily dosing)

Prescribe by brand 
   
Diltiazem Hydrochloride (Adizem-SR)
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Formulary
Green
MR Capsules 90mg, 120mg, 180mg

Prescribe by brand 
   
Diltiazem Hydrochloride (Dilzem SR)
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Formulary
Green
MR Capsules (SR) 60mg
(twice daily dosing)

Prescribe by brand 
   
Nifedipine
View adult BNF View SPC online View childrens BNF
Formulary
Green
Capsules 5mg, 10mg 
   
Nifedipine (Adalat LA)
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Formulary
Green
MR tablets 20mg, 30mg, 60mg
(once daily dosing)

Prescribe by brand 
   
Nifedipine (Adalat Retard)
View adult BNF View SPC online View childrens BNF
Formulary
Green
MR tablets 10mg, 20mg
(twice daily dosing)

Prescribe by brand 
   
Nifedipine (Coracten SR)
View adult BNF View SPC online View childrens BNF
Formulary
Green
MR capsules 10mg
(twice daily dosing)

Prescribe by brand 
   
Verapamil Hydrochloride
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Formulary
Green
Tablets 40mg, 80mg, 120mg;
Injection 5mg/2ml (hospital only) 
   
02.06.03  Expand sub section  Other anitanginal drugs to top
Nicorandil (Ikorel)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
 
Link  Nicorandil (Ikorel): now second-line treatment for angina - risk of ulcer complications
   
Ranolazine (Ranexa)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
  • Consider ranolazine as monotherapy for stable angina if beta blockers and calcium channel blockers cannot be tolerated or both are contraindicated.
  • Consider adding ranolazine if symptoms of stable angina are not controlled with beta blocker or calcium channel blocker monotherapy and the other option (calcium channel blocker or beta blocker) is contraindicated or not tolerated.

See NICE CG126: stable angina
 

 

 
Link  NICE CG126: Stable angina
   
Ivabradine (Procoralan)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber

 
For use by Cardiologists only.

  • for angina in line with NICE CG126
  • for heart failure in line with NICE TA267 
 
Link  NICE CG126: Stable angina
Link  NICE TA267: Ivabradine for treating chronic heart failure
   
02.06.04  Expand sub section  Peripheral vasodilators and related drugs
Naftidrofuryl Oxalate
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Formulary as per NICE TA223 
   
Pentoxifylline (Trental)
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Unlicensed Drug Unlicensed
Green
 
   
02.06.04  Expand sub section  Other preparations used in peripheral vascular disease
 ....
 Non Formulary Items
Amlodipine and Valsartan  (Exforge)

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Non Formulary
 
Cilostazol  (Pletal®)

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Non Formulary
 
Diltiazem Hydrochloride  (Angitil® SR)

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Non Formulary
 
Diltiazem Hydrochloride  (Angitil® XL)

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Non Formulary
 
Diltiazem Hydrochloride  (Calaiard® CR)

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Non Formulary
 
Diltiazem Hydrochloride  (Dilcardia® SR)

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Non Formulary
 
Diltiazem Hydrochloride  (Dilzem XL)

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Non Formulary
 
Diltiazem Hydrochloride  (Slozem)

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Non Formulary
 
Diltiazem Hydrochloride  (Tildem LA)

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Non Formulary
 
Diltiazem Hydrochloride  (Tildem Retard)

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Non Formulary
 
Diltiazem Hydrochloride  (Viazem® XL)

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Non Formulary
 
Diltiazem Hydrochloride  (Zemtard®)

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Non Formulary
 
Felodipine

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Non Formulary
 
Felodipine  (Plendil®)

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Non Formulary
 
Glyceryl Trinitrate  (Nitro-Dur®)

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Non Formulary
 
Glyceryl Trinitrate  (Transiderm-Nitro®)

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Non Formulary
 
Inositol Nicotinate  (Hexopal)

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Non Formulary Tablets 500mg
 
Isosorbide Dinitrate  (Angitak®)

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Non Formulary
 
Isosorbide Dinitrate  (Codocard® Retard)

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Non Formulary
 
Isosorbide Dinitrate  (Isoket®)

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Non Formulary
 
Isosorbide Dinitrate  (Isoket® Retard)

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Non Formulary
 
Isradipine  (Prescal®)

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Non Formulary
 
Lacidipine  (Motens®)

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Non Formulary
 
Lercanidipine Hydrochloride  (Zanidip®)

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Non Formulary
 
Moxisylyte  (Opilon®)

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Non Formulary
 
Nicardipine Hydrochloride  (Cardene®)

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Non Formulary
 
Nicardipine Hydrochloride  (Nicardipine®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Adipine® MR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Adipine® XL)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Cardilate® MR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Cardilate® SR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Fortipine® LA 40)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Hypolar® Retard 20)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Nifedipress® MR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Nifopress® Retard)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nifedipine  (Tensipine® MR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nimodipine  (Nimotop)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nisoldipine  (Syscor® MR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Oxerutins  (Paroven)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Verapamil Hydrochloride  (Cordilox®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Verapamil Hydrochloride  (Half Sucuron® SR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Verapamil Hydrochloride  (Sucuron® SR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Verapamil Hydrochloride  (Univer®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Verapamil Hydrochloride  (Verapress® MR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Verapamil Hydrochloride  (Vertab® SR 240)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber

Medicines which are suitable to be prescribed in primary care only after specialist recommendation. Ongoing prescribing by primary care includes titration of dose and assessment of efficacy. There is no need for ongoing monitoring other than for general adverse effects as listed in the BNF & SPC.  

Amber Shared Care

Medicines which are suitable to be prescribed in primary care only after specialist recommendation only under a shared care protocol once the patient has been stabilised. Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must be approved by the Harrogate & Rurual District Area Prescribing Committee (HaRD APC).   

Black

Medicines which the Harrogate & Rural District Area Prescribing Committee (HaRD APC) has reviewed and does not recommend for use at present based on a review of clinical and/or cost effectiveness data.   

Green

Medicines suitable for routine use and can be prescribed within primary care within their licensed indication in accordance with nationally recognised formularies e.g. BNF, BNF for Children, Palliative Care Formulary. Primary care prescribers take full responsibility for prescribing.  

Grey

Medicines which the Harrogate & Rural District Area Prescribing Committee (HaRD APC) have not yet reviewed.   

Red

Medicines for hospital use only. The responsibility for initiation and monitoring treatment should rest with an appropriate hospital clinician. The drug should be supplied by the hospital for the duration of the treatment course. Primary care prescriber initiation or continuation of treatemnt is not recommended.  

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