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Harrogate & District NHS Foundation Trust
Harrogate & Rural District Clinical Commissioning Group
 
 
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 Formulary Chapter 4: Central nervous system - Full Chapter
Notes:

Guidelines for the Management of Antipsychotic-Induced Hyperprolactinaemia

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04.01  Hypnotics and anxiolytics
04.01.01  Hypnotics
Melatonin
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Restricted Drug Restricted
Amber

Use Circadin tablets - crush and mix with soft food.


For initiation by Consultant Paediatrician only

https://www.tewv.nhs.uk/policy-type/pharmacy/

 
   
Melatonin  (Circadin ®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
MR tablets 2mg

For initiation by Consultant Neurologists only. 
   
04.01.01  Benzodiazepines
Nitrazepam
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Tablets 5mg
Liquid 2.5mg/ml 
   
Controlled Drug Temazepam
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 10mg, 20mg
Liquid 10mg/5ml 
   
04.01.01  Zaleplon, Zolpidem and Zopiclone
Zopiclone
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Tablets 3.75mg, 7.5mg
First choice hypnotic in primary care 
   
04.01.01  Chloral and derivatives to top
Chloral Hydrate
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted Liquid 500mg/5ml

Unlicensed 
   
04.01.01  Clomethiazole (Chlormethiazole)
04.01.01  Antihistamines
04.01.01  Alcohol
04.01.01  Sodium oxybate
04.01.02  Anxiolytics to top
04.01.02  Benzodiazepines
Diazepam
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 2mg, 5mg, 10mg
Liquid 2mg/5ml 
   
Lorazepam
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 1mg
Injection 4mg/ml 
Link  Delerium guidelines for over 65s
   
Chlordiazepoxide Hydrochloride
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted For alcohol detoxification only 
Link  HDFT Guidelines on the management of alcohol withdrawal
   
Oxazepam
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted Tablets 10mg, 15mg

For alcohol detoxification if impaired liver function 
   
04.01.02  Buspirone
04.01.02  Beta blokers
04.01.02  Meprobamate
04.01.03  Barbiturates to top
04.02  Drugs used in psychoses and related disorders
04.02.01  Atypical Antipsychotic Drugs
 note 


Chlorpromazine Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 10mg, 25mg, 50mg, 100mg
Injection 50mg/2ml (hospital only)
Liquid 100mg/5ml 
   
Haloperidol
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 1.5mg, 5mg, 10mg, 20mg
Capsules 500 micrograms
Liquid 2mg/ml
Injection 5mg/ml 
Link  Delerium guidelines for over 65s
   
Sulpiride
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 200mg; Liquid 200mg/5ml 
   
Trifluoperazine
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 1mg, 5mg
Liquid 5mg/5ml 
   
Zuclopenthixol Acetate (Clopixol Acuphase®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
Injection 50mg/ml 
   
Zuclopenthixol Dihydrochloride (Clopixol®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 2mg, 10mg, 25mg 
   
04.02.01  First-Generation Antipsychotic Drugs
04.02.01  Atypical Antipsychotics
Amisulpride
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 50mg, 200mg
Liquid 500mg/5ml 
   
Aripiprazole (Abilify®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 5mg, 10mg, 15mg - Not Stocked

Initiation by Consultant Psychiatrists only, requested through LPG on an individual patient basis. 
   
Clozapine (Clozaril®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
Tablets 25mg, 100mg

Initiation by specialists only.
Patients must be registered with Clozaril monitoring service. 
Link  Safety Guidance - Clozapine on Admission to an Acute Hospital Ward
   
Olanzapine (Zyprexa®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Tablets 2.5mg, 5mg, 10mg
Orodispersible tablets 5mg, 10mg
 
   
Quetiapine (Seroquel®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 25mg, 100mg, 200mg, 300mg 
   
Risperidone (Risperdal®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 500 micrograms, 1mg, 3mg
Liquid 1mg/ml 
   
04.02.02  Antipsychotic depot injections to top
Aripiprazole (Abilify)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber Shared Care
 
Link  TEWV Aripiprazole shared care guideline
   
Flupentixol Decanoate (Depixol®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Injection 12.5mg/0.5ml, 20mg/ml, 25mg/ml, 40mg/2ml, 50mg/0.5ml, 100mg/ml 
   
Fluphenazine Decanoate
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Injection 50mg/0.5ml, 100mg/ml 
   
Haloperidol (Haldol Decanoate®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Injection 50mg/ml, 100mg/ml 
   
Paliperidone (Xeplion)
(Deep intramuscular depot injection)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber Shared Care

50mg, 75mg, 100mg, 150mg prefilled syringe

 
Link  TEWV Paliperidone LAI - shared care guidelines
   
Risperidone (Risperdal Consta®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Injection 25mg, 37.5mg, 50mg 
   
Zuclopenthixol Decanoate (Clopixol®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Injection 200mg/ml, 500mg/ml 
   
04.02.03  Drugs used for mania and hypomania
04.02.03  Benzodiazepines
04.02.03  Antipsychotic drugs
04.02.03  Carbamazepine
04.02.03  Valproic acid to top
Valproic Acid (Depakote®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 250mg 
Link  Drug Safety Update - Pregnancy Prevention Programme Materials online
Link  Drug Safety Update - Valproate contraindicated in women and girls of childbearing potential
   
04.02.03  Lithium
Lithium Carbonate (Priadel®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Shared Care
MR tablets 200mg, 400mg

Specify brand to avoid confusion between different formulations of lithium 
Link  Safety Guidance: Lithium on Admission to an Acute Hospital Ward
Link  TEWV Lithium Shared Care Guidelines
   
Lithium Citrate (Priadel®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber Shared Care
Liquid 520mg/5ml

Specify brand to avoid confusion between different formulations of lithium 
Link  Safety Guidance: Lithium on Admission to an Acute Hospital Ward
   
04.03  Antidepressant drugs
04.03.01  Tricyclic and related antidepressant drugs
04.03.01  Tricyclic antidepressants
Amitriptyline Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 10mg, 25mg, 50mg
Liquid 50mg/5ml 
   
Lofepramine
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 70mg
Liquid 70mg/5ml 
   
04.03.01  Related antidepressants to top
Trazodone Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Green
Capsules 50mg, 100mg
Liquid 50mg/5ml 
   
04.03.02  Monoamine-oxidase inhibitors
04.03.02  Reverible MAOIs
04.03.03  Selective serotonin re-uptake inhibitors
Fluoxetine
View adult BNF View SPC online View childrens BNF
First Choice
Green
Capsules 20mg
Liquid 20mg/5ml 
Citalopram
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 10mg, 20mg
Oral drops 40mg/ml (8 oral drops = 10mg tablet) 
   
Paroxetine
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 20mg, 30mg
Liquid 10mg/5ml 
   
Sertraline
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 50mg, 100mg 
   
04.03.04  Other antidepressant drugs
Mirtazapine
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 15mg, 30mg 
   
Duloxetine (Cymbalta®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Capsules 30mg, 60mg

Only on the advice of a specialist.
Specify brand 
   
Reboxetine (Edronex®)
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 4mg 
   
Venlafaxine (Efexor®)
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 37.5mg, 75mg

(Twice daily dosing)

Doses above 300mg on the advice of a specialist (AMBER-shared care) 
   
Venlafaxine (Efexor® XL)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted Capsules 75mg, 150mg

To be initiated only in patients non-compliant with twice daily dosing.

Doses above 300mg on the advice of a specialist 
   
04.04  CNS stimulants and other drugs used for attention deficit hyperactivity disorder to top
Atomoxetine (Strattera®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber Shared Care
Capsules 10mg

Initiation on the advice of a specialist 
Link  TEWV Atomoxetine shared care guidelines
   
dexamfetamine
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber Shared Care
 
Link  TEWV Dexamfetamine shared care guidelines
   
Guanfacine (Intuniva)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber Shared Care
 
Link  TEWV Guanfacine shared care guidelines
   
Lisdexamfetamine (Elvanse)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber Shared Care
 
Link  TEWV Lisdexamfetamine shared care guidelines
   
Controlled Drug Methylphenidate Hydrochloride (Medikinet)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber Shared Care
Tablets 10mg

Initiation on the advice of a specialist 
Link  TEWV Methylphenidate Shared Care Guidelines
   
Modafinil (Provigil®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber Shared Care

Tablets 100mg

Initiation on the advice of a specialist

 
Link  TEWV Modafanil Shared-Care Guidelines
   
04.04  Cocaine
04.05  Drugs used in the treatment of obesity
04.05.01  Anti-obesity drugs acting on the gastro-intestingal tract
Orlistat (Xenical®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Green
Capsules 120mg

Initiation on the advice of a specialist 
   
04.05.02  Centrally acting appetite suppressants
Rimonabant (Acomplia®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Not stocked at HDFT

Initiation on the advice of a specialist  
   
Sibutramine Hydrochloride (Reductil®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Capsules 10mg

Initiation on the advice of a specialist 
   
04.06  Drugs used in nausea and vertigo to top
04.06  Vomiting during pregnancy
04.06  Postoperative nausea and vomiting
04.06  Motion sickness
04.06  Other vestibular disorders
04.06  Cytotoxic chemotherapy to top
 note  Policy for the use of anti-emetics in patients receiving chemotherapy.
Management of chemotherapy induced mucositis guidelines.

For related guidelines, see Acute Oncology Pathways on the Trust Intranet.
04.06  Palliative care
 note  A guide to symptom management in palliative care - Yorkshire Cancer Network guidelines
04.06  Migraine
04.06  Antihistamines
Cyclizine
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Tablets 50mg
Injection 50mg/ml 
Link  Memorandum - Cyclizine to Ondansetron
   
Promethazine Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 25mg
Liquid 5mg/5ml
Injection 25mg/ml 
   
04.06  Phenothiazines and related drugs
Prochlorperazine
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 5mg
Liquid 5mg/5ml
Injection 12.5mg/ml 
   
Prochlorperazine (Buccastem® (Buccal preparation))
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
 
   
Droperidol (Xomolix®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
Injection 2.5mg/ml

On the advice of a specialist 
   
04.06  Domperidone and metoclopramide to top
Domperidone
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green

Tablets 30mg
Liquid 5mg/5ml
Suppositories 30mg

Domperidone is no longer licensed for those weighing less than 35 kg

 
Link  Drug Safety Update - Dec 2020 - Domperidone for nausea and vomiting: lack of efficacy in children; reminder of contraindications in adults and adolescents
Link  HDFT Domperidone Restriction Memorandum
   
Metoclopramide Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 10mg
Liquid 5mg/5ml
Injection 10mg/2ml 
   
04.06  5HT3 antagonists
Ondansetron
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Tablets 4mg, 8mg
Liquid 4mg/5ml
Injection 4mg/2ml, 8mg/4ml 
   
Granisetron 3.1mg/24 hour patches (Sancuso® )
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Red
Approved for an initial 6 month trial.
Usage to be reviewed by the Area Prescribing Committee in July 2014 
   
Palonosetron with netupitant (Akynzeo®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Approved by HaRD APC April 2017 
   
04.06  Neurokinin receptor antagonist
Fosaprepitant (Ivemend®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
Injection 150mg

Prescribed on the advice of a specialist only pre-chemotherapy
 
   
04.06  Cannabinoid
04.06  Hyoscine
04.06  Other drugs for Ménière's disease to top
Betahistine Dihydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 8mg 
   
04.07  Analgesics
 note 

Suggested Discharge Analgesia for Opioid Naïve Post-op Adult Patients

04.07.01  Non-opioid analgesics
04.07.01  Compound analgesic preparations
Paracetamol
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 500mg, Soluble tablets 500mg
Suppositories 60mg, 120mg, 250mg, 500mg
Liquid 120mg/5ml, 250mg/5ml

Intravenous infusion 10mg/ml*
* Restricted  
Link  Guideline for the dosing of paracetamol in adults
   
Paracetamol and codeine (Co-codamol® 8/500)
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets
Soluble tablets 
   
Paracetamol and codeine (Co-codamol® 30/500)
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 
   
Paracetamol and dihydrocodeine (Co-dydramol®)
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 10/500 
Link  Drug Safety Update - Co-dydramol - Prescribe and dispense by strength
   
Aspirin
View adult BNF View SPC online View childrens BNF
Formulary
Green
Soluble tablets 300mg 
   
04.07.02  Opioid analgesics
 note 

Opioid therapy - patient information leaflet

Controlled Drug Buprenorphine (BuTrans®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green

Patches 5micrograms/hr, 10micrograms/hr,
20micrograms/hr

Once a week patch

Butec is preferred brand in primary care
 
Initiation on the advice of a specialist

 
   
Controlled Drug Buprenorphine (Transtec®)
View adult BNF View SPC online View childrens BNF
Formulary
Green
Patches 35micrograms/hr, 52.5micrograms/hr,
70micrograms/hr

Change every 96 hours

Initiation on the advice of a specialist 
   
Controlled Drug Buprenorphine (Temgesic®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Green
Sublingual tablets 0.4mg, 2mg

 
   
Codeine Phosphate
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Tablets 15mg, 30mg
Liquid 15mg/5ml
Injection 60mg/ml - CONTROLLED DRUG 
   
Codeine Phosphate (Codeine Linctuses)
View adult BNF View SPC online View childrens BNF
Formulary Liquid 15mg/5ml 
   
Controlled Drug Diamorphine Hydrochloride
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Injection 5mg, 10mg, 30mg, 100mg
Intranasal spray (Ayendi®
Link  HDFT Safe and secure handling of intranasal diamorphine SOP
Link  IV diamorphine flow-chart for CCU
   
Dihydrocodeine Tartrate
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 30mg
Liquid 10mg/5ml
Injection 50mg/ml - CONTROLLED DRUG 
   
Controlled Drug Fentanyl
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Patches 12micrograms/hr, 25micrograms/hr,
50micrograms/hr, 75micrograms/hr, 100micrograms/hr

Mezolar is the preferred brand patch in primary care.


Injection 100micrograms/2ml, 500micograms/10ml Hodspital only).

Nasal spray (PecFent) approved as a Green Drug for patients who have failed all other options. 
   
Meptazinol (Meptid®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted Tablets 200mg
Injection 100mg/ml

For use in obstetric analgesia only 
   
Controlled Drug Morphine Sulphate
View adult BNF View SPC online View childrens BNF
Formulary
Green
MR tablets 10mg, 30mg, 60mg, 100mg (Zomorph preferred choice in primary care)
Liquid 10mg/5ml, 100mg/5ml
Injection 10mg/ml, 15mg/ml
Syringe for PCA 50mg/50ml
Oral solution 100micrograms/ml(for use in SCBU) 
Link  Prescribing oral morphine in children for TTOs
   
Controlled Drug Oxycodone Hydrochloride (OxyContin®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Green
MR tablets 5mg, 10mg, 40mg, 80mg

For regular TWICE DAILY dosing

Morphine is first line strong opioid of choice 
   
Controlled Drug Oxycodone Hydrochloride (OxyNorm®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Green
Standard release capsules 5mg, 10mg
(PRN for breakthrough pain)

Liquid 5mg/5ml (250ml bottles)
Liquid 50mg/5ml (120ml bottles)

Injection 10mg/ml, 20mg/2ml, 50mg/ml 
   
Controlled Drug Pethidine Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Green
Injection 50micrograms/ml, 100micrograms/2ml 
   
Tramadol Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Green
Capsules 50mg
Injection 100mg/2ml
MR tablets - restricted to patients non-compliant with regular tramadol 
   
04.07.03  Neuropathic pain to top
Gabapentin
View adult BNF View SPC online View childrens BNF
First Choice
Green
Capsules 100mg, 300mg, 400mg
Liquid 250mg/5ml - reserve for patients with long-term swallowing difficulty or long-term feeding tubes. 
Pregabalin
View adult BNF View SPC online View childrens BNF  Track Changes
Second Choice
Amber
Also approved as an unlicensed indication pre-operatively as part of the gynae enhanced recovery protocol. 
   
04.07.03  Trigeminal neuralgia
Carbamazepine
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 100mg, 200mg
Liquid 100mg/5ml 
   
04.07.03  Postherpetic neuralgia
Amitriptlyine
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 10mg, 25mg, 50mg
Liquid 50mg/5ml 
   
Capsacin
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Green
Cream 0.025%, 0.075%

For initiation by a specialist  
   
04.07.03  Chronic facial pain
04.07.04  Antimigraine drugs
04.07.04.01  Treatment of the acute migraine attack to top
04.07.04.01  Analgesics
04.07.04.01  5HT1 agonists
Sumatriptan
View adult BNF View SPC online View childrens BNF  Track Changes
First Choice
Green
Tablets 50mg
 
04.07.04.01  Ergot alkaloids
04.07.04.01  Anti-emetics
 note  Policy for the use of anti-emetics in patients receiving chemotherapy
04.07.04.01  Other drugs for migrane to top
04.07.04.02  Prophylaxis of migraine
Fremanezumab
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Red

For use in line with NICE guidance

 
Link  NICE TA631 Fremanezumab for preventing migraine
   
Pizotifen
View adult BNF View SPC online View childrens BNF
Formulary
Green
Tablets 500micrograms 
   
04.07.04.03  Cluster headache
04.08  Antiepileptics
04.08.01  Control of epilepsy
 note  http://www.mhra.gov.uk/Safetyinformation/Generalsafetyinformationandadvice/Product-specificinformationandadvice/Product-specificinformationandadvice-A-F/Antiepilepticschangingproducts/index.htm
Brivaracetam  (Briviact®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
Initiation on the advice of a Neurologist 
   
Lacosamide  (Vimpat ® )
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 50mg

Initiation on the advice of a specialist 
   
Perampanel (Fycompa®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
Initiation on the advice of a Specialist 
   
Retigabine (Trobolt®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 50mg, 100mg

Initiation on the advice of a specialist only.
Used as add on treatment in patients with focal onset seizures, which have not been controlled with all other licensed anti-epileptic drug.
Comprehensive eye examination required prior to initiation and then repeated every 6 months. 
Link  MHRA safety warning
   
04.08.01  Partial seizures with or without secondary generalisation to top
04.08.01  Generalised seizures
04.08.01  Carbamazepine and Oxcarbazepine
Carbamazepine
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 100mg, 200mg
MR tablets 200mg, 400mg
Liquid 100mg/5ml
Suppositories 125mg, 250mg

Prescribe by brand 
   
04.08.01  Ethosuximide
Ethosuximide
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
On specialist recommendation only in line with NICE guidance  
   
04.08.01  Gabapentin and pregabalin
Gabapentin
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Capsules 100mg, 300mg, 400mg  
   
Pregabalin
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
 
   
04.08.01  Lacosamide to top
04.08.01  Lamotrigine
Lamotrigine
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 25mg, 50mg, 100mg, 200mg
Dispersible tablets 5mg, 25mg

Initiation on the advice of a Neurologist 
   
04.08.01  Levetiracetam
Levetiracetam
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber

Tablets 250mg, 500mg, 1000mg
Liquid 500mg/5ml
Infusion 500mg/5ml

Initiation on the advice of a Neurologist

 
   
04.08.01  Perampanel
04.08.01  Phenobarbital and other barbiturates
Controlled Drug Phenobarbital
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 30mg
Liquid 50mg/5ml (alcohol free)
Injection 30mg/ml, 200mg/ml 
   
04.08.01  Phenytoin to top
Phenytoin
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Phenytoin sodium
Tablets 100mg, Chewable tablets 50mg
Capsules 25mg, 50mg, 100mg
Injection 250mg/5ml

Phenytoin
Liquid 30mg/5ml

(Phenytoin sodium 100mg = Phenytoin 90mg) 
   
04.08.01  Retigabine
04.08.01  Rufinamide
04.08.01  Tiagabine
Tiagabine (Gabitril®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted Not stocked at HDFT

Initiation on the advice of a Neurologist 
   
04.08.01  Topiramate
Topiramate (Topamax®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
 
   
04.08.01  Valproate to top
Sodium Valproate
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Crushable tablets 100mg
EC tablets 200mg, 500mg
MR tablets 300mg, 500mg
Liquid 200mg/5ml
Injection 300mg/3ml 
Link  Drug Safety Update - Pregnancy Prevention Programme Materials online
Link  Drug Safety Update - Valproate contraindicated in women and girls of childbearing potential
   
04.08.01  Vigabatrin
Vigabatrin (Sabril®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 500mg
Sachets 500mg

Initiation on the advice of a Neurologist 
   
04.08.01  Zonisamide
Zonisamide (Zonegran®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Capsules 25mg, 50mg, 100mg

Initiation on the advice of a Neurologist 
   
04.08.01  Benzodiazepines
Clobazam
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 10mg

Initiation on the advice of a Neurologist 
   
Clonazepam (Rivotril®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 500micrograms

Initiation on the advice of a Neurologist 
   
04.08.01  Other Drugs
04.08.02  Drugs used in status epilepticus to top
Diazepam
View adult BNF View SPC online View childrens BNF
First Choice
Green
Rectal solution 5mg/2.5ml, 10mg/2.5ml
Injection 10mg/2ml
Emulsion injection 10mg/2ml 
Clonazepam (Rivotril®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
Injection 1mg/ml 
   
Lorazepam
View adult BNF View SPC online View childrens BNF
Formulary
Red
Injection 4mg/ml

An unlicensed preparation is currently in use due to a long-term manufacturing problem with the UK licensed injection.

Restricted use  
   
Midazolam (Buccolam®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Buccal liquid - Pre-filled syringes (4)
2.5mg, 5mg, 7.5mg, 10mg

3 to 6 months(Hospital setting) 2.5mg in 0.5ml (Yellow)
>6 months to <1 year 2.5mg in 0.5ml (Yellow)
1 year to <5 years 5mg in 1ml (Blue)
5 years to <10 years 7.5mg in 1.5ml (Purple)
10 years to <18 years 10mg in 2ml (Orange)
 
Link  Information for patients and carers about managing seizures in patients with a cancer affecting their brain
   
04.08.03  Febrile convulsions
Diazepam
View adult BNF View SPC online View childrens BNF
Formulary
Green
Rectal solution 5mg/2.5ml, 10mg/2.5ml
Injection 10mg/2ml (hospital only) 
   
Paracetamol
View adult BNF View SPC online View childrens BNF
Formulary
Green
For formulations see under Analgesics 
   
04.09  Drugs used in parkinsonism and related disorders
 note 

Medicines management of the patient with Parkinsons - HDFT guidelines

04.09.01  Dopaminergic drugs used in Parkinsons disease
 note 

Medicines management of the Parkinsons patient - HDFT guidelines

Parkinsons patients - information for Pharmacists 

04.09.01  Dopamine receptor agonists
Apomorphine Hydrochloride (APO-go®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber Shared Care

Injection 20mg/2ml, 50mg/5ml

Initiation on the advice of a specialist

 
Link  HDFT Apomorphine Prescription Chart
Link  Apomorphine step by step pump set-up guide
Link  Apomorphine - Setting the flow rate guide
Link  Apomorphine abbreviated user guide
Link  Apomorphine Shared Care Guideline - approved for Harrogate Use APC 09/20
   
Cabergoline
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 500micrograms

Initiation on the advice of a specialist 
   
Pramipexole
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
Tablets 180micogram base (= 250micogram salt),
700micogram base (= 1000microgram salt)

Initiation on the advice of a specialist


MR formulation: Individual patient request required through LPG. Preferred product of choice in primary care is Pipexus MR 
   
Ropinirole
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
Tablets 250micrograms, 1mg

Initiation on the advice of a specialist 
   
Ropinirole MR (XL)  (Ipnnia XL®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
2mg, 3mg, 4mg, 6mg and 8mg tablets 
   
Rotigotine (Neupro®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Patches 2mg, 4mg, 6mg, 8mg

Initiation on the advice of a specialist 
   
Apomorphine Hydrochloride (Dacepton®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber Shared Care

Initiation on the advice of a specialist

 
Link  Apomorphine Shared Care Guideline - approved for Harrogate Use APC 09/20
   
04.09.01  Levodopa to top
Co-Beneldopa (Madopar®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Benserazide/levodopa
Capsules 12.5/50, 25/100, 50/200
Dispersible tablets 12.5/50, 25/100
MR capsules 25/100 
   
Co-Beneldopa (Madopar®CR)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
 
   
Co-Careldopa (Half Sinemet ®CR)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
 
   
Co-Careldopa (Sinemet®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Carbidopa/levodopa
Tablets 10/100, 12.5/50, 25/100, 25/250
MR tablets 25/100, 50/200

 
   
Co-Careldopa (Sinemet® CR)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
 
   
Co-Careldopa and Entacapone (Sastravi®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
 
   
04.09.01  Monoamine-oxidase-B inhibitors
Rasagiline (Azilect®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 1mg

Initiation on the advice of a specialist 
   
Selegiline Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 5mg
Liquid 10mg/5ml 
   
04.09.01  Catachol-O-methyltransferase inhibitors
Entacapone (Comtess®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Tablets 200mg 
   
Opicapone (Ongentys® )
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
Approved by the Area Prescribing Committee, January 2017
Second line treatment option for patients unable to tolerate entacapone or where it is contraindicated. 
   
Safinamide (Xadago®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
50mg and 100mg film coated tablets
Approved by the HaRD Area Prescribing Committee December 2016 
   
04.09.01  Amantadine
Amantadine Hydrochloride (Symmetrel®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
 
   
04.09.02  Antimuscarinic drugs used in parkinsonism
Procyclidine Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 5mg
Liquid 5mg/5ml
Injection 10mg/2ml 
   
Trihexyphenidyl Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 2mg, 5mg
Liquid 5mg/5ml

(previously known as benzhexol) 
   
04.09.03  Drugs used in essential tremor, chorea, tics, and related disorders to top
Riluzole (Rilutek®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber Shared Care
Tablets 50mg

Initiation on the advice of a specialist 
Link  HaRD Riluzole Shared Care Guidelines
   
04.09.03  Torsion dystonias and other involuntary movements
Botulinum Toxin Type A (Botox®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
Injection 100units

On the advice of a specialist.

Prescribe by brand 
   
Botulinum Toxin Type A (Dysport®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
Injection 500units

Initiation on the advice of a specialist.

Prescribe by brand 
   
Botulinum Toxin Type B (NeuroBloc®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Red
 
   
Clostridium Botulinum neurotoxin type A (Xeomin®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Red

To be used in line with NICE TA 605 - see link 

Initiation on the advice of a specialist.

Prescribe by brand

 
Link  NICE TA605; Xeomin (botulinum neurotoxin type A) for treating chronic sialorrhoea
   
04.10  Drugs used in substance dependence
04.10  Alcohol dependence
Acamprosate Calcium (Campral EC®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted Tablets 333mg

Initiation on the advice of a Psychiatrist 
   
Disulfiram (Antabuse®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted Tablets 200mg

Initiation on the advice of a Psychiatrist 
   
04.10  Cigarette smoking
 note  Smoking cessation protocol
Nicotine (Niquitin CQ® patches)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Green
Patches, 7mg, 14mg and 21mg strength  
Link  Smoking cessation protocol
   
Varenicline (Champix®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted Tablets 500micrograms, 1mg

 
   
04.10  Opioid dependence to top
Controlled Drug Buprenorphine (Subutex®)
View adult BNF View SPC online View childrens BNF
Restricted Drug Restricted
Amber
Not stocked at HDFT

Initiation on the advice of a Consultant Psychiatrist
 
   
Lofexidine Hydrochloride (BritLofex®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Tablets 200micrograms 
   
Controlled Drug Methadone Hydrochloride
View adult BNF View SPC online View childrens BNF
Formulary
Amber
Mixture 1mg/ml

Initiation on the advice of a Consultant Psychiatrist  
   
04.10.01  Alcohol dependence
Nalmefene (Selincro)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Red
To be prescribed by the community alcohol service provided by North Yorkshire Horizons only. 
   
04.10.02  Nicotine dependence
 note 

Smoking cessation protocol

04.10.03  Opioid dependence
04.10.03  Opioid substitution therapy
04.10.03  Adjunctive therapy and symptomatic treatment to top
04.10.03  Opioid-receptor antagonists
04.11  Dementia
 note 

TEWV Dementia Care Pathway - Guidance for prescribing acetylcholinesterase inhibitors and memantine

Donepezil Hydrochloride (Aricept®)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Green

Tablets 5mg, 10mg

Initiation on the advice of a specialist

 
Galantamine
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
Tablets 12mg
Liquid 4mg/ml

Initiation on the advice of a specialist for patients intolerant to donepezil 
Link  NICE TA217 Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer’s disease
Link  TEWV Dementia Care Pathway - Guidance for prescribing acetylcholinesterase inhibitors and memantine
   
Galantamine (Reminyl® XL)
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
MR capsules 8mg, 16mg, 24mg

Initiation on the advice of a specialist for patients intolerant to donepezil.

MR formulation for patients non-compliant with standard release formulation. 
Link  NICE TA217 Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer’s disease
Link  TEWV Dementia Care Pathway - Guidance for prescribing acetylcholinesterase inhibitors and memantine
   
Memantine Hydrochloride (Ebixa®)
View adult BNF View SPC online View childrens BNF  Track Changes
Formulary
Amber
 
Link  NICE TA217 Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer’s disease
Link  TEWV Dementia Care Pathway - Guidance for prescribing acetylcholinesterase inhibitors and memantine
   
Rivastigmine
View adult BNF View SPC online View childrens BNF  Track Changes
Restricted Drug Restricted
Amber
Capsules 1.5mg
Patches 4.6mg

Initiation on the advice of a specialist.

Patches ONLY for patients unable to take capsules. 
Link  NICE TA217 Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer’s disease
Link  TEWV Dementia Care Pathway - Guidance for prescribing acetylcholinesterase inhibitors and memantine
   
 ....
 Non Formulary Items
Acetazolamide

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Almotriptan  (Almogran®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Alprazolam

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Amantadine Hydrochloride  (Lysovir®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Amitriptyline Hydrochloride and perphenazine  (Triptafen®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Amitriptyline Hydrochloride and perphenazine  (Triptafen-M®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Amobarbital (amylobarbitone) and secobarbital (quinalbarbitone)  (Tuinal®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Amobarbital (amylobrbitone)  (Sodium Amytal®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Analgesics  (Migraleve®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Analgesics  (MigraMax®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Analgesics  (Paramax®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Aprepitant  (Emend®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Aprepitant  (Emend®)

View adult BNF View SPC online View childrens BNF
Non Formulary 3 day pack 80mg & 125mg

Initiation on the advice of a specialist
 
Aspirin and codeine  (Co-codaprin®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Aspirin and papaveretum  (Aspav®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Benperidol  (Anquil®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Benzatropine Mesilate

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Botulinum Toxin Type A  (Azzalure®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Botulinum Toxin Type A  (Vistabel®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Bromocriptine

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Buprenorphine and Naloxone  (Suboxone®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Bupropion Hydrochloride  (Zyban®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Buspirone Hydrochloride

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Butobarbital (butobarbitone)  (Soneryl®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Cabamazepine

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Cabergoline  (Cabaser®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Cannabis oil and related products

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Black
 
Chloral Hydrate  (Chloral Elixir®, Paediatric, BP 2000)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Chloral Hydrate 300mg in 5mL

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Cinnarizine

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Clomethiazole  (Heminevrin®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Clomipramine Hydrochloride

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Clomipramine Hydrochloride  (Anafranil® SR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Clonidine Hydrochloride

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Cloral Betaine  (Welldorm®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Co-Careldopa  (Duodopa®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Dexamfetamine Sulphate  (Dexedrine®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Dextromoramide

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Dihydrocodeine Tartrate  (DHC Continus®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Dolasetron Mesilate  (Anzemet®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Dosulepin Hydrochloride
(No longer recommended by NICE because of increased cardiac risk and toxicity in overdose)

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Black
Tablets 75mg
Capsules 25mg
Liquid 75mg/5ml
 
Doxepin  (Sinepin®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Eletriptan  (Relpax®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Ergotamine Tartrate  (Cafergot®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Ergotamine Tartrate  (Migril®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Escitalopram  (Cipralex®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Eslicarbazepine  (Zebinix®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Fentanyl  (Effentora®)
(Palliative care use only)

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Red
 
Controlled Drug  Fentanyl  (Instanyl®)
(palliative care use only)

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Black
 
Fentanyl lozenge  (Actiq®)
(palliative care use only)

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Black
 
Flupentixol  (Depixol®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Flupentixol Decanoate  (Depixol® Conc.)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Flupentixol Decanoate  (Depixol® Low Volume)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Fluphenazine Decanoate  (Modecate® Concentrate)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Fluphenazine Hydrochloride  (Moditen®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Flurazepam  (Dalmane®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Fluvoxamine Maleate  (Faverin®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Fluvoxamine Maleate  (Fluvoxamine®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Fosphenytoin Sodium  (Pro-Epanutin®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Frovatriptan  (Migrad®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Granisetron  (Kytril®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Haloperidol

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Hydromorphone Hydrochloride  (Palladone®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Hydromorphone Hydrochloride  (Palladone® SR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Hyoscine Hydrochloride  (Scopoderm® TTS)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Imipramine Hydrochloride

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Isocarboxazid

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Isometheptene Mucate  (Midrid®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Ketamine

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Levodopa

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Levomepromazine  (Nozinan®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Lisuride Maleate

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Lithium Carbonate  (Camcolit®)

View adult BNF View SPC online View childrens BNF
Non Formulary Tablets 250mg

Specify brand to avoid confusion between different formulations of lithium
 
Lithium Carbonate  (Liskonum®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Lithium Citrate  (Li-Liquid®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Loprazolam

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Meprobamate

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Methylphenidate Hydrochloride  (Concerta® XL)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Methylphenidate Hydrochloride  (Equasym® XL)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Methylphenidate Hydrochloride  (Ritalin®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Methysergide  (Deseril®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Metoclopramide Hydrochloride  (Maxolon® High Dose)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Metoclopramide Hydrochloride  (Maxolon® SR)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Mianserin Hydrochloried  (Mianserin®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Moclobemide

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Morphine Salts  (Sevredol®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Morphine Salts  (Zomorph®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Controlled Drug  Morphine Salts and cyclizine  (Cyclimorph®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Nabilone

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Naltrexone (low dose)

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Black

UKMI Q+A: low dose naltrexone for MS

 
Naltrexone Hydrochloride  (Nalorex®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Naltrexone Hydrochloride  (Opizone®)

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Non Formulary
 
Naratriptan  (Naramig®)

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Non Formulary
 
Nefopam Hydrochloride  (Acupan®)

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Non Formulary
 
Nicotine  (Nicotinell®)

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Non Formulary
 
Nicotine  (NiQuitin® CQ)

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Non Formulary
 
Nortriptyline  (Allegron®)

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Non Formulary
 
Olanzapine Embonate  (ZypAdhera®)

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Non Formulary
Red
 
Orphenadrine Hydrochloride

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Non Formulary
 
Oxcarbazepine  (Trileptal®)

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Non Formulary
 
Palonosetron  (Aloxi®)

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Non Formulary
Red
 
Controlled Drug  Papaveretum

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Non Formulary
 
Controlled Drug  Papaveretum  (Papaveretum with Hyoscine Injection)

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Non Formulary
 
Paracetamol and codeine  (Co-codamol ®15/500)

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Non Formulary
 
Paracetamol and dihydrocodeine  (Remedeine®)

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Non Formulary
 
Paracetamol and methionine  (Pardote®)

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Non Formulary
 
Paraldehyde

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Non Formulary
 
Controlled Drug  Pentazocine

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Non Formulary
 
Pergolide

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Non Formulary
 
Pericyazine  (Neilactil®)

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Non Formulary
 
Perphenazine

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Non Formulary
 
Perphenazine  (Fentazin®)

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Non Formulary
 
Controlled Drug  Pethidine Hydrochloride and promethazine  (Pamergan® P100)

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Non Formulary
 
Phenelzine  (Nardil®)

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Non Formulary
 
Controlled Drug  Phenobarbital Sodium

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Non Formulary
 
Phenytoin

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Non Formulary
 
Pimozide  (Orap®)

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Non Formulary
 
Pipotiazine Palmitate  (Piportil® Depot)

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Non Formulary
 
Piracetam  (Nootropil®)

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Non Formulary
 
Primidone  (Mysoline®)

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Non Formulary
 
Prochlorperazine

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Non Formulary
 
Promazine Hydrochloride  (Promazine®)

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Non Formulary
 
Promethazine Hydrochloride

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Non Formulary
 
Rizatriptan  (Maxalt®)

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Non Formulary
 
Ropinirole  (Adartrel®)

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Non Formulary
 
Rufinamide  (Inovelon®)

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Non Formulary
 
Controlled Drug  Secobarbital (quinalbarbitone)  (Seconal Sodium® )

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Non Formulary Capsules 50mg
 
Sertindole  (Serdolect®)

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Non Formulary
 
Sodium Oxybate  (Xyrem®)

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Non Formulary
 
Sodium Valproate  (Epilim® Chrono)

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Non Formulary
 
Sumatriptan  (Imigran® Radis)

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Non Formulary
 
Tapentadol modified relase tablets  (Palexia SR)

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Non Formulary
Grey


Controlled Drug Schedule 2
 
tapentadol tablets  (Palexia)

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Grey


Controlled Drug Schedule 2
 
Controlled Drug  Targinact (Oxycodone/Naloxone)  (Targinact®)

View adult BNF View SPC online View childrens BNF Track Changes
Non Formulary
Black
 
Tetrabenazine  (Xenazine® 25)

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Non Formulary
 
Tolcapone  (Tasmar®)

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Non Formulary
 
Tolfenamic Acid  (Clotam®)

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Non Formulary
 
Tramadol Hydrochloride  (Dromadol®SR)

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Non Formulary
 
Tramadol Hydrochloride  (Larapam® SR)

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Non Formulary
 
Tramadol Hydrochloride  (Zamadol® SR)

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Non Formulary
 
Tramadol Hydrochloride  (Zydol® SR)

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Non Formulary
 
Tramadol Hydrochloride  (Zydol® XL)

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Non Formulary
 
Tramadol Hydrochloride and paracetamol  (Tramacet®)

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Non Formulary
Black
 
Tranylcypromine

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Non Formulary
 
Triclofos Sodium  (Triclofos® oral Solution BP (Triclofos Elixir))

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Trimipramine  (Surmontil®)

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Non Formulary
Black
 
Tropisetron  (Navoban®)

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Non Formulary
 
Trytophan  (Optimax®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Venlafaxine  (Foraven XL®)

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Non Formulary
 
Venlafaxine  (Venaxx XL®)

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Non Formulary
 
Venlafaxine  (Venlalic® XL)

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Non Formulary
 
Zaleplon  (Sonata®)

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Non Formulary
 
Zolmitriptan  (Zomig®)

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Non Formulary
 
Zolpidem Tartrate  (Stilnoct®)

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Non Formulary
 
Zolpidem Tartrate  (Zolpidem®)

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Non Formulary
 
Zotepine  (Zoleptil®)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
Zuclopenthixol Decanoate  (Clopixol® Conc.)

View adult BNF View SPC online View childrens BNF
Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber

Medicines which are suitable to be prescribed in primary care only after specialist recommendation. Ongoing prescribing by primary care includes titration of dose and assessment of efficacy. There is no need for ongoing monitoring other than for general adverse effects as listed in the BNF & SPC.  

Amber Shared Care

Medicines which are suitable to be prescribed in primary care only after specialist recommendation only under a shared care protocol once the patient has been stabilised. Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must be approved by the Harrogate & Rurual District Area Prescribing Committee (HaRD APC).   

Black

Medicines which the Harrogate & Rural District Area Prescribing Committee (HaRD APC) has reviewed and does not recommend for use at present based on a review of clinical and/or cost effectiveness data.   

Green

Medicines suitable for routine use and can be prescribed within primary care within their licensed indication in accordance with nationally recognised formularies e.g. BNF, BNF for Children, Palliative Care Formulary. Primary care prescribers take full responsibility for prescribing.  

Grey

Medicines which the Harrogate & Rural District Area Prescribing Committee (HaRD APC) have not yet reviewed.   

Red

Medicines for hospital use only. The responsibility for initiation and monitoring treatment should rest with an appropriate hospital clinician. The drug should be supplied by the hospital for the duration of the treatment course. Primary care prescriber initiation or continuation of treatemnt is not recommended.  

netFormulary